I’d second that. Both the wah and LBM should be plugged into before plugging into the amp. The fx loop on the 65R isn’t great to begin with, but if I were forced to use it I might put a delay or reverb in the loop, not the wah and definitely not distortion.

Distortion pedals aren’t designed to go in the FX loop – they are designed to take a dry guitar signal, crunch it up into the distorted sound, so the amp’s preamp stage can round off the edges and make it sound like a distorted guitar.

It’ll be difficult to get a sound like the EHX demo because it sounds to me like they are using a very expensive british voiced tube amp (65amps soho???) with a slight bit of natural overdrive which is adding to the sound of the pedal somewhat, but that doesn’t mean to say you won’t get a good sound – as julian said, if you’re struggling to get any definition amongst all the fuzz, roll back the sustain knob a little – it can work wonders, i have mine at 8 o’clock (Very low) on my NYC muff. Although i’m sure you’ll notice you’re much closer to the sound you hear on online demos by simply having the pedal in front of the amp

I never run any pedals in amp fx loops……they are really designed to put rack equipment in, not stomp boxes.

I know some people do, but I don’t.

I agree, although I would change ‘should’ to ‘could’

Yeah. . .
my amp doesn’t have a loop
so I don’t run anything in the loop
and I’m fine
but then again I’ve got a silverface bassman
it’s clean at 10

Pretty sure you can. I like to imagine J Mascis lives in a fort made entirely of variations of Big Muffs.